AXXAM

Posters

(if interested in receiving a copy of the posters please contact us)

Simon Hilcove, Scott Schachtele, Ali Fathi, Jing Lu, Stella Donato, Dolores Del Prete, Fernanda Ricci, Silvia Cainarca, & Coby Carlson
Modeling Parkinson’s Disease in 2D + 3D: Evaluating α-Synuclein Aggregation, Autophagy, and Neural Network Activity
International Society for Stem Cell Research (ISSCR) annual meeting 2023 (June 14-17, 2023) – poster based on the collaboration between Axxam and FUJIFILM Cellular Dynamics, Inc., (Madison, USA)

Lucia Rutigliano, Dolores Del Prete, Stella Donato, Salvatore Corallino, Coby Carlson, Ali Fathi, Scott Schachtele, Paola Tarroni, Lia Scarabottolo, Andrea Faedo, Fernanda Ricci, Silvia Cainarca
Aggregation and neurodegeneration: partners in crime
AD/PD 2023, Gothenburg, Sweden (March 28-April 1, 2023) – in collaboration FUJIFILM Cellular Dynamics, Inc., (Madison, USA)

Juan Florez, Samuel Bradberry, Marusa Kustec, Lucia Rutigliano, Guillaume Lemercier, Silvia Cainarca, Alessandro Marchesini, Stephan Heyse, Cinzia Nucci, Stephan Steigele
A robust data analysis workflow for highly scalable, routine application of calcium oscillation assays
Genedata Biopharma Partner Symposium, Boston (March 9-10, 2023) – in collaboration with Genedata AG (Basel, Switzerland)

Elena Sirtori, Jean Francois Rolland, Riccardo Rizzetto, Elena Laura Budusan, Jan Rathje, Maria Giustina Rotordam, Tom A. Goetze, Nadine Becker, Alison Obergrussberger, Aaron Randolph, Andrea Brüggemann, Michael George, Niels Fertig
Pharmacology of P2X 3 and P2X 2/3 receptors: An automated patch clamp study
Biophysical Society Annual Meeting, San Diego (February 18-22) – in collaboration with the University of Queensland (Brisbane, Australia), Nanion Technologies (Munich, Germany) and Nanion Technologies Inc, (New Jersey, USA)

Lucia Azzollini, Dolores Del Prete, Christoph Klimek, Gernot Wolf, Alvaro Ingles-Prieto, Lia Scarabottolo
An imaging-based assay for a challenging target: the case of SLC30A8
3rd REsolution and 7th RESOLUTE Consortia Meetings, Berlin (October 19, 2022) – in collaboration with CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences

Hilaria Mollica, Paola Bonetti, Katharina Montag, Lucia Rutigliano, Silvia Cainarca, Paola Tarroni, Lia Scarabottolo, Stefan Lohmer and Fernanda Ricci
An integrated platform for drug screening of neurological disease models
Elrig UK, Drug Discovery, London (October 4- 5, 2022)

Maria Barthmes, Riccardo Rizzetto, Andre Bazzone, Anna Mondini, Jean-Francois Rolland, Niels Fertig, Michael George, Andrea Brüggemann
A novel approach to detect electrogenic transporter activity in intact cells applied to investigate iPSC derived cardiomyocytes and neurons
Biophysical Society Annual Meeting, San Diego, USA (February 15-19, 2020) – in collaboration with Nanion Technologies GmbH

Manuel Paina, Jim Goodchild, Lucy Firth, Katharina Montag, Maria Grazia Giribaldi, Loredana Redaelli, Lia Scarabottolo, Judith Blythe, Jean-Francois Rolland
Identifying ryanodine receptor modulators: From high-throughput screening to single channel recording
Biophysical Society Annual Meeting, San Diego, USA (February 15-19, 2020) – in collaboration with Syngenta Limited

Sara Tremolada, Antonella Larovere, Andrea Faedo, Loredana Redaelli, Lia Scarabottolo
Fluorescent dyes and sensors for cell-based assays – WP3
2nd Resolute Consortium Meeting, Krems, Austria (June 3-5, 2019)

Salvatore Corallino, Francesca Sassone, Loredana Redaelli, Giovanna Maresca, Laura Montanini, Marcella De Silvestris, Lia Scarabottolo
Generation of robust cell-based assays for a set of SLCs – WP6
2nd Resolute Consortium Meeting, Krems, Austria (June 3-5, 2019)

Paola Picardi, Marcella De Silvestris, Andrea Lauri, Laura Montanini, Lucia Azzollini, Marina Martina, Loredana Redaelli, Paola Tarroni, Russell Thomas, Lia Scarabottolo, Stefan Lohmer
TREM2: pSYK as tool for a cell-based assay, suitable for HTS
PHAGO 3rd General Assembly, Ludwigshafen, Germany (October 22-24, 2018)

Lucia Rutigliano, Christina Kuhn, Fernanda Ricci, Anjia Nitzsche, Simone Haupt, Andrea Faedo, Paola Tarroni, Katharina Montag, Silvia Cainarca, Lia Scarabottolo
Human iPSC-derived cells: a powerful tool for neuropathic pain disease modelling
10th Anniversary IMI Scientific Symposium, Bruxelles, Belgium (October 22-23, 2018)
NGN-PET project – This project has received funding from the Innovative Medicines Initiative 2 Joint Undertaking under grant agreement No 116072. This Joint Undertaking receives support from the European Union’s Horizon 2020 research and innovation programme and EFPIA

Gianluca Conti, Valeria Wanke, Mariantonietta Rubino, Patrizia Arioli, Ulf Brüggemeier, Daniele Carettoni
Development of a RORγ-CoAP interaction assay based on TR-FRET suitable for HTS
EMBO Workshop – Nuclear receptors and biological networks, Kolymbari, Crete, Greece (September 11-15, 2018)

Gaël Stéphant, Céline Bouquet, Catherine Cancian, Viviana Agus, Lia Scarabottolo, Loredana Redaelli, Anne Douar, Didier Pruneau
A robust, highly sensitive cell-based assay for potency measurement of the AAV-vectorizedoptogenetictherapy, GS030-DP, developed to treat retinitis pigmentosa
American Society of Gene and Cell Therapy (ASGCT) Annual Meeting, Chicago (May 16-19, 2018)

Lucia Rutigliano, Riccardo Rizzetto, Kevin Oelstrom, Lia Scarabottolo, Stefan Lohmer and Silvia Cainarca
Calcium players at work in human iPSC-derived glutamatergic cultures (iCell® GlutaNeurons)
iForum, London (September 28, 2017)

Paola Picardi, Andrea Faedo, Katharina Montag, Cinzia Nucci, Loredana Redaelli, Lia Scarabottolo, Stefan Lohmer
Metabolic pathologies with high medical needs: research and development of new pharmacological approaches and innovative molecular targets
EMBO conference, Autophagy: From molecular principles to human diseases, Cavtat-Dubrovnik, Croatia (September 25-29, 2017)

Nazareno Menegatti, Paolo Pevarello, Michela Stucchi, Russell Thomas, Lia Scarabottolo.
AXXDIV3.0 a next generation screening collection
MipTec 2017, Basel Life, Basel, Switzerland (September 10-13, 2017)

Jason C.G. Halford, Jo Harrold (Department of Psychological Sciences, University of Liverpool, United Kingdom), Lia Scarabottolo (Axxam, Italy), Massimo Marzorati (Prodigest, Belgium), Rianne Ruijschop (Nizo, Netherlands), Alexandra Johnstone (Rowett Institute, Aberdeen, UK), John Blundell, Graham Finlayson (Institute of Psychological Sciences, University of Leeds, Leeds, UK), Anders Sjödin (Department of Nutrition, Exercise and Sports, University of Copenhagen, Denmark).
SATIN: SATiety INnovation, Satiety Control through Food Structures made by Novel Processing

Loredana Redaelli, Giovanna Maresca, Sara Tremolada, Christina Kuhn, Matteo Brioschi, Dietmar Hess, Elke Guenther, Lia Scarabottolo.
NeuroSafe: a human integrated in vitro neurotoxicity safety platform
Safety Pharmacology Society 2015, 15th Annual Meeting, Prague, Czech Republic (September 28 – October 1, 2015)

Viviana Agus, Alberto Di Silvio, Jean-Francois Rolland, Anna Mondini, Sara Tremolada, Katharina Montag, Lia Scarabottolo, Loredana Redaelli, Stefan Lohmer.
Optogenetics applied to the High Throughput Screening: novel cellular assays controlled by light
MipTec 2015, The International Life Science Exhibition, Basel, Switzerland (September 22-24, 2015)

Andrea Menegon, Viviana Agus, Daniela Crespi, Jean-Francois Rolland, Loredana Redaelli, Lia Scarabottolo, Pierfausto Seneci, Nausicaa Mazzocchi, Massimo Imberti, Cecilia Poli, Antonella Lanati, Fabio Grohovaz.
Validation of a new optical method for ion channel screening
MipTec 2015, The International Life Science Exhibition, Basel, Switzerland (September 22-24, 2015)

Christer Wiik-Nielsen, Lynsey MacIntyre, Laura Stucchi, Louise Young, Grainne Abbott, Michele Stanley, Cheng Cheng, Ute Hentschel Humeida, John Day, Elin Aksnes, Ruangelie Edrada-Ebel, Daniele Carettoni.
An integrated lead discovery programme within SeaBioTech to address major parasitic infections in aquaculture
9th European Marine Natural Products Conference, Glasgow, UK (August 30 – September 2, 2015)

Cheng Cheng, Lynsey MacIntyre, Usama Ramadan Abdelmohsen, Hannes Horn, Paraskevi Polymenakou, Daniele Carettoni, Ruangelie Edrada-Ebel, Ute Hentschel Humeida.
Discovery of biologically active compounds from marine sponge-associated actinomycetes
9th European Marine Natural Products Conference, Glasgow, UK (August 30 – September 2, 2015)

Viviana Agus, Alberto Di Silvio, Sara Tremolada, Katharina Montag, Anna Mondini, Jean-Francois Rolland, Lia Scarabottolo, Loredana Redaelli, Stefan Lohmer.
“Lighting up” high throughput screening: how optogenetics will impact the future of drug discovery
Optogenetics, Keystone Symposia, Denver, USA (March 12-16, 2015)

Cinzia Nucci, Giuliana Piazza, Alberto di Silvio, Anna Mondini, Jean-Francois Rolland, Michela Stucchi.
Application of an optogenetic tool to study Cav1.3 blockers
SLAS2015, 4th Annual Conference & Exhibition, Washington DC, USA (February 7-11, 2015)

Katharina Montag, Marcel Winnig, Barbara Zanone Poma, Giovanna Maresca, Matteo Brioschi, Jean-Francois Rolland, Loredana Redaelli, Lia Scarabottolo, Doris Hafenbradl.
Generation of cell-based assays by genome editing approaches
MipTec 2014, The Leading European Event for Drug Discovery, Basel, Switzerland (September 23-25, 2014)

Vanessa Nardese, Maria Cristina Sidoli, Valeria Wanke, Mariantonietta Rubino, Daniele Carettoni.
To make a short story long: recombinant expression and HTS assay development for complex multi-domain protein kinases
MipTec 2014, The Leading European Event for Drug Discovery, Basel, Switzerland (September 23-25, 2014)

Alberto di Silvio, Sara Tremolada, Jean-Francois Rolland, Elena Sirtori, Katharina Montag, Viviana Agus, Sabrina Corazza, Loredana Redaelli, Lia Scarabottolo, Michela Stucchi, Stefan Lohmer.
A bright future where optogenetics meet with voltage gated ion channels
SLAS2014, 3rd Annual Conference & Exhibition, San Diego, USA (January 19-22, 2014)

Alberto di Silvio, Elena Sirtori, Marcella De Silvestris, Katharina Montag, Giuliana Piazza, Viviana Agus, Daniela Crespi, Maria Grazia Giribaldi, Loredana Redaelli, Jean-Francois Rolland, Lia Scarabottolo.
A fully integrated platform for a P2RX drug discovery process
SLAS2014, 3rd Annual Conference & Exhibition, San Diego, USA (January 19-22, 2014)

Laura Stucchi, Barbara Zanone Poma, Maria Grazia Giribaldi, Loredana Redaelli, Sabrina Corazza, Lia Scarabottolo.
SATIN: SATiety INnovation – Development of an in vitro platform to identify satiating food components.
SLAS2014, 3rd Annual Conference & Exhibition, San Diego, USA (January 19-22, 2014)

Jason Halford, Michele Kellerhals, Alvin Ibarra on behalf of the SATIN Consortium Partners and the SATIN Advisory Board.
Satiety Control through Food Structures made by Novel Processing: The SATIN (SATiety INnovation) Project
European Congress on Obesity ECO2013, Liverpool, UK (May 12-15, 2013)

Giovanna Maresca, Maria Grazia Giribaldi, Viviana Agus, Anna Della Bella, Sara Tremolada, Katharina Montag, Vanessa Nardese, Matteo Brioschi, Sabrina Corazza, Lia Scarabottolo, Loredana Redaelli, Bernd Kalthof.
A cell-based assay for the identification of endothelial Nitric Oxide Synthase (eNOS) post-transcriptional stabilizers
SLAS2013, 2nd Annual Conference & Exhibition, Orlando, USA (January 12-16, 2013)

Marcel Winnig, Viviana Agus, Daniela Crespi, Maria Grazia Giribaldi, Giovanna Maresca, Katharina Montag, Loredana Redaelli, Doris Hafenbradl, Lia Scarabottolo.
GCaMP: a new tool for sensing intracellular Ca2+ level increase in cell-based assays used in drug discovery programs
SLAS2013, 2nd Annual Conference & Exhibition, Orlando, USA (January 12-16, 2013)

Barbara Zanone Poma, Loredana Redaelli, Giuliana Piazza, Cinzia Nucci, Michela Stucchi, Lorena Za, Mara Zippoli, Andrea Beccari, Doris Hafenbradl, Chiara Liberati.
chAMPion-based HTS and Hit follow-up activities on TGR5, an attractive  target for the metabolic syndrome
SLAS2013, 2nd Annual Conference & Exhibition, Orlando, USA (January 12-16, 2013)

Alberto di Silvio, Angela Molteni, Cinzia Nucci, Viviana Agus, Loredana Redaelli, Alessandro Taddei, Nazareno Menegatti, Lia Scarabottolo, Sabrina Corazza, Michela Stucchi.
Identification of Cav1.3 channel blockers as novel therapeutic agents
SLAS2013, 2nd Annual Conference & Exhibition, Orlando, USA (January 12-16, 2013)

Barbara Zanone Poma, Loredana Redaelli, Chiara Liberati, Sabrina Corazza, Lucia Iuzzolino, Andrea Rossignoli, Silvia Cainarca, Michela Stucchi, Simone Lorenzi, Andrea Beccari, Lia Scarabottolo.
chAMPion helps Screening: case study on CB2 receptor
SBS 17th Annual Conference & Exhibition, Orlando, USA (April 27-31, 2011)

Lia Scarabottolo, Alberto Di Silvio, Cinzia Nucci, Angela Molteni, Viviana Agus, Alessandro Taddei, Michela Stucchi.
Smarter screening for tricky targets: NaV1.7 sodium channel and thallium dyes
SBS 17th Annual Conference & Exhibition, Orlando, USA (April 27-31, 2011)

Barbara Zanone Poma, Daniele Carettoni, Loredana Redaelli, Lucia Iuzzolino, Andrea Rossignoli, Michela Stucchi, Chiara Liberati, Simone Lorenzi, Andrea Beccari, Lia Scarabottolo.
Identification of Novel Selective CB2 Agonists for Pain Treatment through an HTS Campaign with chAMPion Technology
SBS 16th Annual Conference & Exhibition, Phoenix, USA (April 11-15, 2010)

Viviana Agus, Alessandro Taddei, Sabrina Corazza, Loredana Redaelli, Vincent Dupriez, David Handfield, Lucille Beaudet, Lia Scarabottolo.
A High-Throughput Luminescence-Based Assay for CRAC Channel Inhibitors Identification
SBS 16th Annual Conference & Exhibition, Phoenix, USA (April 11-15, 2010)

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