AXXAM

Event

Ion Channels satellite meeting at Biophysical Society Annual Meeting (BPS 2026)

Michael Campognone, SVP, BD – North America

Jean-Francois Rolland,  Director, Biological Sciences

Anna Mondini, 

Head, Electrophysiology

Advancing ion channel drug discovery with electrophysiology and integrated screening

Axxam is attending Drug Discovery for Ion Channels XXVI, the satellite meeting of the Biophysical Society Annual Meeting 2026, dedicated to the latest advances in ion channel biology and drug discovery.

Ion channels are among the most challenging and impactful drug targets, requiring functional, high‑resolution approaches to truly understand mechanism of action and compound effects. Axxam supports ion channel drug discovery by combining state‑of‑the‑art electrophysiology, innovative organellar electrophysiology, and integrated discovery workflows designed to generate biologically meaningful data early in research programs.

Why ion channels require functional discovery approaches

Ion channels regulate essential physiological processes, and their dysfunction is implicated in a wide range of neurological, cardiovascular, and rare diseases. Traditional screening methods often fail to capture the dynamic and biophysical nature of ion channel activity.

Electrophysiology remains the gold standard for ion channel research, providing direct measurement of ionic currents and functional modulation. When integrated with scalable screening and profiling strategies, it enables more confident decision‑making in early drug discovery.

Electrophysiology and organellar electrophysiology at Axxam

We offer comprehensive electrophysiology capabilities to support ion channel programs from target validation to lead discovery.

Electrophysiology Platforms

Functional assays designed to interrogate ion channel activity with high precision and flexibility.

  • Manual and automated patch‑clamp platforms for detailed functional and mechanistic characterization of ion channels
  • Multi‑electrode array (MEA) recordings to assess population‑level and network electrical activity in relevant cellular models
  • Flexible assay formats tailored to voltage‑ and ligand‑gated ion channels

Pioneers in Organellar Electrophysiology

Innovative approaches enabling the study of ion channels and transporters directly within intracellular organelles.

  • LysoPatch for electrophysiological recordings from lysosomes
  • NucleoPatch to investigate ion channels at the nuclear membrane
  • MitoPatch for functional analysis of mitochondrial ion transport

These unique platforms allow investigation of ion channel function in native subcellular environments, opening new opportunities to explore disease mechanisms and therapeutic modulation beyond the plasma membrane.

Meet us at Drug Discovery for Ion Channels XXVI

Drug Discovery for Ion Channels XXVI brings together experts from academia, biotech, pharma, and technology providers to share insights and advances in the field.

We look forward to connecting with researchers and discovery teams to discuss how Axxam’s electrophysiology and organellar electrophysiology platforms can support ion channel drug discovery programs.

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