Popescu AS, Butler CA, Allendorf DH, Piers TM, Mallach A, Roewe J, Reinhardt P, Cinti A, Redaelli L, Boudesco C, Pradier L, Pocock JM, Thornton P, Brown GC, “Alzheimer’s disease-associated R47H TREM2 increases, but wild-type TREM2 decreases, microglial phagocytosis of synaptosomes and neuronal loss“, Glia, Wiley Online Library,

Boudesco C, Nonneman A, Cinti A, Picardi P, Redaelli L, Swijsen S, Roewe J, Reinhardt P, Ibach M,Walter J, Pocock JM, Ren Y, Driguez PA, Dargazanli G, Eyquem S, Proto J, Flores-Morales A, Pradier L, “Novel potent liposome agonists of triggering receptor expressed on myeloid cells 2 phenocopy antibody treatment in cells“, Glia.2022;70:2290–2308,

Peixoto Pinheiro B, Müller M, Bös M, Guezguez J, Burnet M, Tornincasa M, Rizzetto R, Rolland JF, Liberati C, Lohmer S, Adel Y, Löwenheim H, “A potassium channel agonist protects hearing function and promotes outer hair cell survival in a mouse model for age-related hearing loss“, Cell Death Dis. 2022 Jul 11;13(7):595. doi: 10.1038/s41419-022-04915-5

Bianchini G, Tomassetti M, Lillini S, Sirico A, Bovolenta S, Za L, Liberati C, Novelli R, Aramini A, “Discovery of Novel TRPM8 Blockers Suitable for the Treatment of Somatic and Ocular Painful Conditions: A Journey through pKa and LogD Modulation“, J Med Chem. 2021 Nov 11. doi: 10.1021/acs.jmedchem.1c01647

Apolloni S, Fabbrizio P, Amadio S, Napoli G, Freschi M, Sironi F, Pevarello P, Tarroni P, Liberati C, Bendotti C, Volonté C, “Novel P2X7 Antagonist Ameliorates the Early Phase of ALS Disease and Decreases Inflammation and Autophagy in SOD1-G93A Mouse Model”, Int. J. Mol. Sci. 2021, 22, 10649. ttps:// 10.3390/ijms221910649

Dvorak V, Wiedmer T, Ingles-Prieto A, Altermatt P, Batoulis H, Bärenz F, Bender E, Digles D, Dürrenberger F, Heitman LH, IJzerman AP, Kell DB, Kickinger S, Körzö D, Leippe P, Licher T, Manolova V, Rizzetto R, Sassone F, Scarabottolo L, Schlessinger A, Schneider V, Sijben HJ, Steck AL, Sundström H, Tremolada S, Wilhelm M, Muelas MW, Zindel D, Steppan CM and Superti-Furga G, “An overview of cell-based assay platforms for the solute carrier family of transporters”, Front. Pharmacol., 10 August 2021,

Wißfeld J, Mathews M, Mossad O, Picardi P, Cinti A, Redaelli L, Pradier L, Brüstle O, Neumann H, “Reporter cell assay for human CD33 validated by specific antibodies and human iPSC-derived microglia”, Scientific Reports 11, 13462 (2021). doi: 10.1038/s41598-021-92434-2

Agus V, Flak TA, Picardi P, Pizzi S, Rutigliano L, Cainarca S, Redaelli L, Rolland J-F, Scarabottolo L, “Parallel all-optical assay to study use-dependent functioning of voltage-gated ion channels in a miniaturized format”, SLAS Discov., 2020

Agus V, Janovjak H, “All-Optical Miniaturized Co-culture Assay of Voltage-Gated Ca2+ Channels”. In: Niopek D. (eds) Photoswitching Proteins. Methods in Molecular Biology, (2020) vol 2173, pp247-260. Humana, New York, NY

Gemei M, Talarico C, Brandolini L, Manelfi C, Za L, Bovolenta S, Liberati C, Del Vecchio L, Russo R, Cerchia C, Allegretti M, Beccari AR, “Binding Mode Exploration of B1 Receptor Antagonists’ by the Use of Molecular Dynamics and Docking Simulation – How Different Target Engagement Can Determine Different Biological Effects”, Int. J. Mol. Sci. 2020, 21, 7677

Ranieri R, Ciaglia E, Amodio G, Picardi, Proto MC, Gazzerro P, Laezza C, Remondelli P, Bifulco M, Pisanti S, “N6-isopentenyladenosine dual targeting of AMPK and Rab7 prenylation inhibits melanoma growth through the impairment of autophagic flux”, Cell Death & Differentiation (13 October 2017) doi:10.1038/cdd.2017.165

Sartori L, Mercurio C, Amigoni F, Cappa A, Fagá G, Fattori R, Legnaghi E, Ciossani G, Mattevi A, Meroni G, Moretti L, Cecatiello V, Pasqualato S, Romussi A, Thaler F, Trifiró P, Villa M, Vultaggio S, Botrugno OA, Dessanti P, Minucci S, Zagarrí E, Carettoni D, Iuzzolino L, Varasi M, Vianello P., “Thieno[3,2-b]pyrrole-5-carboxamides as New Reversible Inhibitors of Histone Lysine Demethylase KDM1A/LSD1. Part 1: High-Throughput Screening and Preliminary Exploration”, J Med Chem. 2017 Mar 9;60(5):1673-1692

Agus V, Picardi P, Scarabottolo L, Lohmer S., “Three-Dimensional Control of Ion Channel Function through Optogenetics and Co-Culture”, SLAS Discov. 2017 Aug 1:2472555217722990. doi: 10.1177/2472555217722990. (Epub ahead of print)

Menegon A, Pitassi S, Mazzocchi N, Redaelli L, Rizzetto R, Rolland JF, Poli C, Imberti M, Lanati A, Grohovaz F., “A new electro-optical approach for conductance measurement: an assay for the study of drugs acting on ligand-gated ion channels”,
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Agus V, Janovjak H., “Optogenetic methods in drug screening: technologies and applications”, Curr Opin Biotechnol. 2017 Mar 5;48:8-14. doi: 10.1016/j.copbio.2017.02.006. (Epub ahead of print)

Pevarello P, Bovolenta S, Tarroni P, Za L, Severi E, Torino D, Vitalone R., “P2X7 antagonists for CNS indications: recent patent disclosures”Pharm Pat Anal 6 (2), 61-76. 2017

López-Nicolás R, Marzorati M, Scarabottolo L, Halford JCG, Johnstone AM, Frontela-Saseta C, Sanmartín AM, Ros-Berruezo G, Harrold JA., “Satiety Innovations: Food Products to Assist Consumers with Weight Loss, Evidence on the Role of Satiety in Healthy Eating: Overview and In Vitro Approximation”, Current Obesity Reports 2016, DOI 10.1007/s13679-016-0196-9

Bayin NS, Frenster JD, Kane JR, Rubenstein J, Modrek AS, Baitalmal R, Dolgalev I, Rudzenski K, Scarabottolo L, Crespi D, Redaelli L, Snuderl M, Golfinos JG, Doyle W, Pacione D, Parker EC, Chi AS, Heguy A, MacNeil DJ, Shohdy N, Zagzag D, Placantonakis DG., “GPR133 (ADGRD1), an adhesion G-protein-coupled receptor, is necessary for glioblastoma growth”, Oncogenesis. 2016 Oct 24;5(10):e263. doi: 10.1038/oncsis.2016.63. PubMed PMID: 27775701

Mistretta F, Russo A, Castiglione F, Bettiga A, Colciago G, Montorsi F, Brandolini L, Aramini A, Bianchini G, Allegretti M, Bovolenta S, Russo R, Benigni F, Hedlund P., DFL23448, a novel TRPM8-selective ion channel antagonist, modifies bladder function and reduces bladder overactivity in awake rats” The Journal of Pharmacology and Experimental Therapeutics 2016 Jan; 356(1):200-11

Formicola R, Pevarello P, Kuhn C, Liberati C, Piscitelli F, Sodano M., “FFA4/GPR120 agonists: a survey of the recent patent literature”, Pharmaceutical Patent Analyst. 2015 Nov; 4(6):443-51

Pevarello P, Cainarca S, Liberati C, Tarroni P, Piscitelli F, Severi E., “Patent Review Ca2+ release-activated Ca2+ channel inhibitors“, Pharmaceutical Patent Analyst. 2014, Vol. 3, No. 2, Pages 171-182, DOI 10.4155/ppa.14.7 (doi:10.4155/ppa.14.7)

Fluegge D, Moeller LM, Cichy A, Gorin M, Weth A, Veitinger S, Cainarca S, Lohmer S, Corazza S, Neuhaus EM, Baumgartner W, Spehr J, Spehr M., “Mitochondrial Ca2+ mobilization is a key element in olfactory signaling”, Nat Neurosci. 2012 Mar 25; 15(5):754-62

Tarroni P, Villa C, Mrak E, Zolezzi F, Mattioli M, Gattuso C, Rubinacci A.“Microarray analysis of 1,25(OH)(2) D(3) regulated gene expression in human primary osteoblasts”, J Cell Biochem. 2012 Feb; 113(2):640-9

Veitinger S, Veitinger T, Cainarca S, Fluegge D, Engelhardt CH, Lohmer S, Hatt H, Corazza S, Spehr J, Neuhaus EM, Spehr M., “Purinergic Signaling Mobilizes Mitochondrial Ca2+ in Mouse Sertoli Cells”, J Physiol. 2011 Nov 1; 589

Haddock SH, Mastroianni N, Christianson LM., “A photoactivatable green-fluorescent protein from the phylum Ctenophora”, Proc Biol Sci. 2010 Apr 22; 277(1685):1155-60. Epub 2009 Dec 16

Cainarca S, Fenu S, Bovolenta S, Arioli P, Menegon A, Lohmer S, Corazza S., “From c-Photina mouse embryonic stem cells to high-throughput screening of differentiated neural cells via an intermediate step enriched in neural precursor cells”, J Biomol Screen. 2010 Oct; 15(9):1132-43. Epub 2010 Sep 10

Cainarca S, Fenu S, Ferri C, Nucci C, Arioli P, Menegon A, Piemonti L, Lohmer S, Wrabetz L, Corazza S., “A Photoprotein in Mouse Embryonic Stem Cells Measures Ca2+ Mobilization in Cells and in Animals”, PLoS ONE. 2010 Jan 27; 5(1): e8882

Carettoni D, Verwaerde P., “Enzymatic assays for high-throughput screening”, In Abraham DJ ed. Burger’s Medicinal Chemistry and Drug Discovery, 7th edition. John Wiley and Sons.Epub. April 2010

Oger F, Lecorgne A, Sala E, Nardese V, Demay F, Chevance S, Desravines DC, Aleksandrova N, Le Guével R, Lorenzi S, Beccari A, Barath P, Hart DJ, Bondon A, Carettoni D, Simonneaux G, Salbert G., “Biological and biophysical properties of the histone deacetylase inhibitor suberoylanilide hydroxamic acid are affected by the presence of short alkyl groups on the phenyl ring”, J Med Chem. 2010 Mar 11; 53(5):1937-50

Corazza S, Erik J. Wade., “A Practical Guide to Assay Development and High-Throughput Screening in Drug Discovery”, Chapter 10 Book in Assay Development Using Primary and Primary-like Cells: Taylor and Francis (2009)

Grazio D, Pichler I, Fuchsberger C, Zolezzi F, Guarnieri P, Heidegger H, Scherer A, Engl B, Messini S, Egarter-Vigl E, Pramstaller PP., “Differential gene expression analysis of ovarian cancer in a population isolate”, Eur J Gynaecol Oncol. 29(4):357-63 (2008)

Tasdemir A, Khan F, Jowitt TA, Iuzzolino L, Lohmer S, Corazza S, Schmidt TJ., “Engineering of a monomeric fluorescent protein AsGFP499 and its applications in a dual translocation and transcription assay”Protein Eng Des Sel, Oct; 21(10):613-22 (2008)

Herrmann M, Selige J, Raffael S, Sachs G, Brambilla A, Klein T., “Systematic expression profiling of the gastric H+/K+ ATPase in human tissue”, Scand J Gastroenterol. Nov; 42(11):1275-88 (2007)

Bovolenta S, Foti M, Lohmer S, Corazza S., “Development of a Ca2+ – activated photoprotein, Photina, and its application to high-throughput screening”, J Biomol Screen, Aug; 12(5):694-704 (2007)

Brambilla A, Tarroni P., “The GeneTrawler: mapping potential drug targets in human and rat tissues”, Expert Opin Ther Targets, Apr;11(4):567-80 (2007)

Corazza S, Scarabottolo L, Lohmer S, Liberati C., “An innovative cell-based assay for the detection of modulators of soluble guanylate cyclase”, Assay Drug Dev Technol, Apr; 4(2):165-73 (2006)

Bovolenta S, Corazza S., “Ca2+ Signal Detection in HTS: improved reporting for agonists and antagonists of GPCRs and ion channels”, Genetic Engineering & Biotechnology News; Aug 1, 26 (14) (2006)

Corazza S., “Screening with Bioluminescence” ,PharmaTechnology; Autumn, 26-29 (2006)

Redaelli L, Zolezzi F, Nardese V, Bellanti B, Wanke V, Carettoni D., “A platform for high-throughput expression of recombinant human enzymes secreted by insect cells”, J Biotechnol, Oct 17; 120(1):59-71 (2005)

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