High Content Assays
High content image-based analysis represents an effective strategy to study disease-relevant processes in the complex
physiological environment of the cells. Independently of the disease area (neurobiology, oncology, immunology, rare disease, metabolism, etc.), this approach allows validation of the relevant mechanism of action of drugs and/or targets through extraction of the rich information present in biological images at the cellular and subcellular levels.
Our high-content platforms include several assays investigating, in automated and miniaturized format, the most significant functions linked to human pathophysiology, such as autophagy, mis-localization, DNA damage, pathological aggregates and several others. Available off-the-shelf assays can be accessed and customized to specific needs and new assays can also be generated upon request for screening purposes.
Our high content assay platform
Our platforms include relevant cell models for neurodegeneration diseases (such as Alzheimer’s and Parkinson’s), neuropathic pain, inflammation diseases, degradation pathways and many more. Disease-relevant models can also be tailored thanks to our state-of-the-art gene editing tools and reporter systems generation.
Our image-based assays
Check below the phenotypic assays you can get access to at Axxam and contact us to find more information:
Aggregation Assays – Apoptosis – Autophagy – Biomolecular Condensates – Cell Cycle Assays – Cell Painting – Colony Assays – Cytotoxicity – DNA Damage – Endocytosis – Expression Level – Localization Analysis – Migration Assays – Mitochondrial Assays – Mitophagy – Neurite Outgrowth – Phagocytosis – Spheroid Assays