The selection of optimal hits holds immense importance in drug discovery, exerting a profound influence on the downstream program success. By increasing the likelihood of identifying the best-suited hit compound, minimizing time and cost, mitigating the future risk of failure and enhancing the prospects of developing a successful drug candidate, this critical process shapes the trajectory of drug development. Our wide range of in-house drug discovery capabilities aim to equip our clients with comprehensive insights into their hits supporting their further decision-making process.
Hit qualification package
Let your hit take the highway to the lead!
Our hit qualification package offers a comprehensive solution for meticulously evaluating hits identified through High-Throughput Screening (HTS), providing our clients with vital information to make well-informed decisions regarding hit selection and follow-up activities.
With more than 10 years experience in early-stage drug discovery, and a broad therapeutic area expertise (e.g. inflammation, CNS disorders and oncology), a dedicated team of medicinal chemists will support you in giving value to your hits and in turn de-risk the subsequent drug development process. Our MedChem team will offer expert advice and guidance for hit prioritization, qualification and pharmacophore studies, through the following range of services:
Establish the game plan - sooner is better!
Expanding the chemical space around hits, by using analogs which are commercially available or designed and synthesized ad hoc, to understand emerging principles of the underlying structure-activity relationship, together with determining their basic physico-chemical and ADME properties will provide essential information for hit prioritization.
Download the flyer below for an overview of our medicinal chemistry solutions to select qualified hits:
Click below to learn how we support our clients in the Hit-to-Lead journey: