Discovery Solutions
Focusing on the first steps of the drug discovery process, our work to identify bioactive molecules with the desired pharmacological activity, such as the modulation of a target or a cellular pathway, is fundamental to pave the way toward the development of new drug compounds.
While our services from target validation to lead generation can be shortly described in three blocks, assay development, High-throughput screening and profiling/Hit-to-lead, those include a variety of activities to be taken care of.
We have units and scientists specialised in each step of the process, but all of them collaborate to provide our clients with the best strategy to tackle even the most challenging project.
Core expertise at Axxam
Cell Biology
Cell-based assay development
Off-the-shelf assays
Optogenetics readout
Biochemistry
Cell-free assay development
Enzymatic & molecular interaction
Biophysical methods (TSA)
Molecular Biology
Construct generation
Genome editing
RNA biology platforms
High Content Screening
High content assay development
Phenotypic screening
Cell Painting
Electrophysiology
Automated/manual patch-clamp
Organellar patch-clamp
Multi electrode array (MEA)
High-Throughput Screening
Optical, ephys, imaging, gene expression readouts
Automation expertise
Compound Profiling
Cell-based; cell-free compound profiling
SAR campaigns
Proof of principle
Analytical Services & MedChem
Small molecule quality check
Hit qualification
Med-chem consultancy
Compound Management
Storage and maintenance
Compound plate reformatting
Compound libraries
Cell Factory
Cell culture
Primary cell lines
AXXSense
Taste & olfaction biology
NatPure compound collection
Bitterness prediction
We understand your needs and provide solutions
Our research teams work closely with client scientists to translate project objectives into research plans.