Dark Genome Target Discovery & Development

The dark genome—including non-coding DNA and poorly characterized gene families—has traditionally been overlooked. Today, it represents one of the most promising frontiers in drug discovery, with the potential to unlock treatments for complex and underserved diseases.

Key topics at the conference include:

• Functional genomics and annotation of the dark genome

• Target discovery using CRISPR, AI, and multi-omics platforms

• Strategies to drug previously “undruggable” targets

• Translating novel biology into preclinical candidates

• Case studies from pharma and biotech