High Content Screening Insights
High content screening (HCS), also known as phenotypic screening, is a powerful approach that combines cell based assays and
image analysis to study and characterize the effect of bioactive compounds on biological pathways within complex cellular
environment.
High content screening (HCS), also known as phenotypic screening, is a powerful approach that combines cell based assays and
image analysis to study and characterize the effect of bioactive compounds on biological pathways within complex cellular
environment.
- Relevant cell models for neuropathic pain: primary and iPS-derived sensory neurons
- Assessing pathological aggregates
- Neurite outgrowth analysis to reveal neurotoxicity
- Neuro-inflammation related to activation of glial cells
- Pro-inflammatory markers
- Assessment for compounds able to modulate the quantity of condensates and aggregates in cells
- DNA damage repair assay
Key information from phenotypic analysis
