Discovery Services
Focusing on the first steps of the drug discovery process, our work to identify bioactive molecules with the desired
pharmacological activity, such as the modulation of a target or a cellular pathway, is fundamental to pave the way toward the
development of new drug compounds.
While our services from target validation to lead generation can be shortly described in three blocks, assay development,
High-Throughput Screening and profiling/Hit-to-Lead, those include a variety of activities to be taken care of. We have units
and scientists specialised in each step of the process, but all of them collaborate to provide our clients with the best strategy
to tackle even the most challenging project.
Operational units at Axxam
Molecular Biology
Construct generation
Genome editing
RNA biology platforms
Biochemistry
Cell-free assay development
Enzymatic & P-P/P-DNA/P-RNA interaction
Biophysical methods (TSA/MST)
Cell Biology
Cell-based assay development
Off-the-shelf assays
Optogenetics readout
Electrophysiology
Automated patch-clamp
Manual patch-clamp
Organellar patch-clamp
High Content
High content assay development
Phenotypic screening
Cell Painting
High-Throughput Screening
Optical, ephys, imaging, gene expression readouts
Compound libraries
Compound Management
Storage and maintenance
Compound plate reformatting
Data Sciences
HTS Data Analysis
Chemoinformatic analysis
Consultancy
Analytical Services & MedChem
Small molecule quality check
Hit validation
Med-Chem Consultancy
We understand your needs and provide solutions
Our research teams work closely with client scientists to translate project objectives into research plans.