AXXAM

Networking Event

Science and Networking

iPSC Assay Development and Screening - a Synergistic Story

Co-organized by Axxam, Fujifilm Cellular Dynamics and Hamamatsu Photonics:

Scientific seminar and networking

Join us for a scientific seminar focused on induced Pluripotent Stem Cells.

Hamamatsu, Fujifilm Cellular Dynamics Inc. (FCDI), and Axxam S.p.A. are pleased to present a seminar showcasing iPSC integration into key components of clinically translatable early drug discovery.

Successfully translating early drug discovery efforts to the clinic requires,

      • Access to patient-based and disease-relevant material and models,
      • High-throughput functional screening
      • An ability to interrogate and integrate across model systems and modalities to generate actionable clinically relevant data.

This seminar will showcase advancements and case-studies on these topics with an emphasis on cardiovascular and neurodegeneration discovery efforts.

Attendees will enjoy a light lunch and refreshments and have an excellent opportunity for networking with colleagues, peers, and subject-matter experts as they learn about the intersection of high-throughput functional screening, clinically relevant disease models, and successful integration into drug discovery campaigns. 

Agenda

13.00-13.30         WELCOME AND REFRESHMENT

13.30-13.45          High throughput screening of iPSC using the Hamamatsu FDSSµcell

                                   (Diana Kovalauskaite. HAMAMATSU)

13.45-14.30          iPSC-based models for drug discovery; 2D, 3D, and complex models with immune           

                                      compartments across cardiac, hepatic, and neural therapeutic areas

                                     (Blake Anson. FCDI)

          • Developing patient-based and disease-linked human models.
          • Incorporating iPSC models across 2D, 3D, and complex-culture formats.
          • Specific case-studies in cardiac safety, neurodegeneration, and incorporating immune-based cells (macrophage and microglia).

14.30-14.50          COFFEE BREAK

14.50-15.40          iPSC-based assays for Drug Discovery: a comprehensive screening platform

                                     (Atf Nagbou and Silvia Cainarca. Axxam)

          • General capabilities with a focus on:
          • Miniaturization and adaptation to automation
          • Developing iPSC-based assays for drug screening, using different type o cells, including neurons and cardiomyocytes
          • Setting up of relevant disease models (PD, AD, ALS)

15.40-16.00          NETWORKING AND COCKTAIL HOUR

 

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